How is smallpox spread?
Smallpox is spread from one person to another by infected saliva droplets that expose a susceptible person having face-to-face contact with the ill person. Persons with smallpox are most infectious during the first week of illness, because that is when the largest amount of virus is present in saliva. However, some risk of transmission lasts until all scabs have fallen off.

Show All Answers

1. What is smallpox?
2. When was the last case of smallpox reported in the United States?
3. What is the incubation period for smallpox?
4. What are the symptoms of smallpox?
5. How is smallpox spread?
6. Is a smallpox vaccine available?
7. Is there a treatment for smallpox?